BC Environmental and Occupational Health Research Network

The specific objectives of the research are to understand the determinants of epigenetic changes, the role of DNA methylation in cancer risk and factors that modify DNA methylation and cancer relationship in existing human population studies.
Specific research areas of interest include, but are not limited to, the following themes:
• Determinations of the roles of physical, chemical, and infectious agents and behavioral factors on the types and levels of DNA methylation changes in human populations of different races and ethnicities;
• Determination of the role(s) of DNA methylation changes in the risk of cancer in human populations; and
• Identifications of genetic, environmental, and host susceptibility factors that modify the risk of cancer associated with DNA methylation alterations in different races and ethnic groups.