BC Environmental and Occupational Health Research Network

The purpose of this Funding Opportunity Announcement (FOA) for R01 applications is to encourage clinicians, epidemiologists, geneticists, statisticians, and translational cancer control and prevention researchers to improve existing models for cancer risk, prognosis, or response to therapy by developing innovative research projects that: use existing data; develop new models for cancer risk and prognosis; and validate new models and evaluate their utility in research and clinic settings. This FOA is designed to provide a mechanism under which investigators can address two major challenges in model development, which are: integrating diverse types of data (e.g., clinical, demographic, pathologic, environmental, epidemiologic, outcomes, and genetic data from varied data marts or warehouses); and ensuring adequate validation (i.e., using multiple separate populations to define sensitivity, specificity, and positive and negative predictive values). Using the NIH Research Project Grant R01 funding mechanism, this FOA focuses on well developed projects supported by preliminary data.