DCC Pilot & Feasibility Opportunities in 2011

Agency: 
JDRF

The DCC is currently soliciting P&F proposals that advance the mission of the consortium.
Current areas of interest include, but are not limited to:
Application of stem cells, including induced pluripotent stem (iPS) cells and regenerative therapies to the repair and reversal of diabetic complications.
Expanded in vivo efficacy studies for preclinical validation of promising new therapeutics for diabetic complications.
• Assessment of multiple complications in model systems (C.elegans, zebrafish, drosophila, etc).
• Testing the role of genes or loci that arise from ongoing human genetics/sequencing efforts.
• Use of relevant model systems to accelerate gene X environment (GEI) studies.
• Interrogation of existing clinical samples or resources with DNA analysis, omics, histology and pathology as well as looking for circulating blood and urine biomarkers.
• Linking and coordination of existing databases relevant to complications research.
• Inclusion of other co-morbidities of diabetes and obesity including non alcoholic fatty liver disease, gastrointestinal complications, peripheral vascular disease and wound healing.
Budget requests should be commensurate with project needs over a one year project period. While average DCC P&F awards are $60,000 Total Costs for one year, well justified requests for support of up to $100,000 Total Costs per year will be considered.

Deadline: 
May 16, 2011

Last updated April 15, 2011